Visual performance with an extended depth of focus contact lens for myopia control and corneal topography in assessing lens centration.

Increasing in myopia prevalence worldwide led to develop control strategies to slow down myopia progression. One option is represented by extended depth of focus (EDOF) contact lens (CL) to control retinal defocus. Decentration in EDOF CLs can decrease the quality of vision. This study was carried out to evaluate accuracy and repeatability of the centration assessment of EDOF CLs using corneal topography, and to compare the visual performance of EDOF with a control single vision CL. For each EDOF CL, a topography over the CL and a slit lamp (SL) digital picture were taken. For the SL images, a software was used to assess the position of the lens; for the topography acquisitions, the position was detected using a qualitative procedure, by two observers and repeated after 15 days. Visual acuity (VA), with both lenses, was evaluated at high and low contrast. After the analysis, the accuracy of the topographic assessment with respect to SL assessment resulted good. Intra- and inter-observer reliability of the measurement were good, but the clinical experience of the observer affected the repeatability of the method. VA with EDOF CLs was significantly lower compared to single vision CL.